Auraptene
From Wikipedia, the free encyclopedia
| Auraptene | |
|---|---|
 |
|
| IUPAC name | 7-((E)-3, 7-Dimethylocta-2, 6-dienyloxy)-2H-chromen-2-one |
| Other names | Aurapten 7-Geranyloxycoumarin |
| Identifiers | |
| CAS number | [495-02-3] |
| PubChem | |
| SMILES | CC(=CCC/C(=C/COC1=CC2=C(C=C1)C=CC(=O)O2)/C)C |
| Properties | |
| Molecular formula | C19H22O3 |
| Molar mass | 298.38 g mol-1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus. Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models.[1] The effect in humans is not yet known.
[edit] References
- ^ Curini, M., Carvotto, G., Epifano, F. and Giannone, G. "Chemistry and Biological Activity of Natural and Synthetic Prenyloxycoumarins"(2006). Current Medicinal Chemistry, 13, 199-222.
