Aryl-acylamidase

From Wikipedia, the free encyclopedia

In enzymology, an aryl-acylamidase (EC 3.5.1.13) is an enzyme that catalyzes the chemical reaction

an anilide + H₂O a carboxylate + aniline

Thus, the two substrates of this enzyme are anilide and H₂O, whereas its two products are carboxylate and aniline.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl-acylamide amidohydrolase. Other names in common use include AAA-1, AAA-2, brain acetylcholinesterase (is associated with AAA-2), and pseudocholinesterase (associated with arylacylamidase).

[edit] References

• IUBMB entry for 3.5.1.13
• BRENDA references for 3.5.1.13 (Recommended.)
• PubMed references for 3.5.1.13
• PubMed Central references for 3.5.1.13
• Google Scholar references for 3.5.1.13
• Nimmo-Smith RH (1960). "Aromatic N-deacylation by chick-kidney mitochondria". Biochem. J. 75: 284–293. 

[edit] External links

The CAS registry number for this enzyme class is 9025-18-7.

• IUBMB entry for 3.5.1.13

• KEGG entry for 3.5.1.13

• BRENDA entry for 3.5.1.13

• NiceZyme view of 3.5.1.13

• EC2PDB: PDB structures for 3.5.1.13

• PRIAM entry for 3.5.1.13

• PUMA2 entry for 3.5.1.13

• IntEnz: Integrated Enzyme entry for 3.5.1.13

• MetaCyc entry for 3.5.1.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047680: aryl-acylamidase

• AMIGO entry for GO code 0047680: aryl-acylamidase