ARMCX3

From Wikipedia, the free encyclopedia


Armadillo repeat containing, X-linked 3
Identifiers
Symbol(s) ARMCX3; KIAA0443; ALEX3; DKFZp781N1954; MGC12199; dJ545K15.2
External IDs OMIM: 300364 MGI: 1918953 HomoloGene: 9588
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 51566 71703
Ensembl ENSG00000102401 ENSMUSG00000049047
Uniprot Q9UH62 Q8BHS6
Refseq NM_016607 (mRNA)
NP_057691 (protein)		 NM_027870 (mRNA)
NP_082146 (protein)
Location Chr X: 100.76 - 100.77 Mb Chr X: 130.1 - 130.11 Mb
Pubmed search [1] [2]

Armadillo repeat containing, X-linked 3, also known as ARMCX3, is a human gene.[1]

This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.[1]

[edit] References

  1. ^ a b Entrez Gene: ARMCX3 armadillo repeat containing, X-linked 3.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Kurochkin IV, Yonemitsu N, Funahashi SI, Nomura H (2001). "ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.". Biochem. Biophys. Res. Commun. 280 (1): 340–7. doi:10.1006/bbrc.2000.4125. PMID 11162520. 
  • Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.". Mol. Vis. 8: 205–20. PMID 12107410. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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