ARMCX1

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Armadillo repeat containing, X-linked 1
Identifiers
Symbol(s) ARMCX1; ALEX1; DKFZp686P06199
External IDs OMIM: 300362 MGI: 1925498 HomoloGene: 9589
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 51309 78248
Ensembl ENSG00000126947 ENSMUSG00000033460
Uniprot Q9P291 Q9CX83
Refseq NM_016608 (mRNA)
NP_057692 (protein)		 NM_030066 (mRNA)
NP_084342 (protein)
Location Chr X: 100.69 - 100.7 Mb Chr X: 130.06 - 130.07 Mb
Pubmed search [1] [2]

Armadillo repeat containing, X-linked 1, also known as ARMCX1, is a human gene.[1]

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.[1]

[edit] References

  1. ^ a b Entrez Gene: ARMCX1 armadillo repeat containing, X-linked 1.

[edit] Further reading

  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325-37. doi:10.1038/nature03440. PMID 15772651. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kurochkin IV, Yonemitsu N, Funahashi SI, Nomura H (2001). "ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.". Biochem. Biophys. Res. Commun. 280 (1): 340-7. doi:10.1006/bbrc.2000.4125. PMID 11162520. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
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