ARL8B

From Wikipedia, the free encyclopedia

ADP-ribosylation factor-like 8B

PDB rendering based on 1zd9.

Available structures: 1zd9, 2al7, 2h18

Identifiers

Symbol(s)

ARL8B; ARL10C; FLJ10702; Gie1

External IDs

MGI: 1914416 HomoloGene: 10056

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • GTP binding • GDP binding • alpha-tubulin binding • beta-tubulin binding
Cellular Component:	• intracellular • cytoplasm • membrane • midbody • spindle midzone
Biological Process:	• chromosome segregation • small GTPase mediated signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018184 (mRNA)
NP_060654 (protein)

NM_026011 (mRNA)
NP_080287 (protein)

Location

Chr 3: 5.14 - 5.2 Mb

Chr 6: 108.75 - 108.79 Mb

Pubmed search

[1]

[2]

ADP-ribosylation factor-like 8B, also known as ARL8B, is a human gene.^[1]

[edit] References

^ Entrez Gene: ARL8B ADP-ribosylation factor-like 8B.

[edit] Further reading

Bagshaw RD, Callahan JW, Mahuran DJ (2006). "The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.". Biochem. Biophys. Res. Commun. 344 (4): 1186-91. doi:10.1016/j.bbrc.2006.03.221. PMID 16650381.
Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.". J. Cell. Sci. 119 (Pt 8): 1494-503. doi:10.1242/jcs.02958. PMID 16537643.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621-5. doi:10.1126/science.1105776. PMID 15761153.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J. Cell. Sci. 117 (Pt 20): 4705-15. doi:10.1242/jcs.01347. PMID 15331635.
Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.". J. Biol. Chem. 279 (17): 17126-33. doi:10.1074/jbc.M310097200. PMID 14871887.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.