Apo-beta-carotenoid-14',13'-dioxygenase

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In enzymology, an apo-beta-carotenoid-14',13'-dioxygenase (EC 1.13.12.12) is an enzyme that catalyzes the chemical reaction

8'-apo-beta-carotenol + O₂ 14'-apo-beta-carotenal + H₂O

Thus, the two substrates of this enzyme are 8'-apo-beta-carotenol and O₂, whereas its two products are 14'-apo-beta-carotenal and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is 8'-apo-beta-carotenol:O2 oxidoreductase.

[edit] References

• IUBMB entry for 1.13.12.12
• BRENDA references for 1.13.12.12 (Recommended.)
• PubMed references for 1.13.12.12
• PubMed Central references for 1.13.12.12
• Google Scholar references for 1.13.12.12
• Dmitrovskii AA, Gessler NN, Gomboeva SB, Ershov YuV, Bykhovsky VYa (Mosc). "Enzymatic oxidation of beta-apo-8'-carotenol to beta-apo-14'-carotenal by an enzyme different from beta-carotene-15,15'-dioxygenase". B Biochemistry.: 787–92. PMID 9331970. 

[edit] External links

• IUBMB entry for 1.13.12.12

• KEGG entry for 1.13.12.12

• BRENDA entry for 1.13.12.12

• NiceZyme view of 1.13.12.12

• EC2PDB: PDB structures for 1.13.12.12

• PRIAM entry for 1.13.12.12

• PUMA2 entry for 1.13.12.12

• IntEnz: Integrated Enzyme entry for 1.13.12.12

• MetaCyc entry for 1.13.12.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050588: apo-beta-carotenoid-14',13'-dioxygenase

• AMIGO entry for GO code 0050588: apo-beta-carotenoid-14',13'-dioxygenase