Apigenin 4'-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an apigenin 4'-O-methyltransferase (EC 2.1.1.75) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,7,4'-trihydroxyflavone, whereas its two products are S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Other names in common use include flavonoid O-methyltransferase, and flavonoid methyltransferase. This enzyme participates in flavonoid biosynthesis.

[edit] References

• IUBMB entry for 2.1.1.75
• BRENDA references for 2.1.1.75 (Recommended.)
• PubMed references for 2.1.1.75
• PubMed Central references for 2.1.1.75
• Google Scholar references for 2.1.1.75
• Kuroki G and Poulton JE (1981). "The para-O-methylation of apigenin to acacetin by cell-free extracts of Robinia pseudoacacia L". Z. Naturforsch. C: Biosci. 36: 916–920. 

[edit] External links

The CAS registry number for this enzyme class is 118251-36-8.

• IUBMB entry for 2.1.1.75

• KEGG entry for 2.1.1.75

• BRENDA entry for 2.1.1.75

• NiceZyme view of 2.1.1.75

• EC2PDB: PDB structures for 2.1.1.75

• PRIAM entry for 2.1.1.75

• PUMA2 entry for 2.1.1.75

• IntEnz: Integrated Enzyme entry for 2.1.1.75

• MetaCyc entry for 2.1.1.75

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030754: apigenin 4'-O-methyltransferase

• AMIGO entry for GO code 0030754: apigenin 4'-O-methyltransferase