Antagomir

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Antagomirs are one of a novel class of chemically engineered oligonucleotides.[1] Antagomirs are used in the silencing of endogenous microRNA.[2]

[edit] References

  1. ^ Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. (Dec 2005). "Silencing of microRNAs in vivo with 'antagomirs'". Nature 438 (7068): 685–9. doi:10.1038/nature04303. PMID : 16258535. 
  2. ^ Czech Michael P (2006). "MicroRNAs as Therapeutic Targets". New England Journal of Medicine 354 (11): 2. doi:10.1056/NEJMcibr060065. PMID 16540623. 
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