ANAPC10

From Wikipedia, the free encyclopedia

Anaphase promoting complex subunit 10

PDB rendering based on 1jhj.

Available structures: 1jhj

Identifiers

Symbol(s)

ANAPC10; DOC1; APC10; DKFZP564L0562

External IDs

MGI: 1916249 HomoloGene: 32238

Gene ontology
Molecular Function:	• ubiquitin-protein ligase activity • protein binding
Cellular Component:	• anaphase-promoting complex
Biological Process:	• regulation of progression through cell cycle • G2/M transition of mitotic cell cycle • mitotic anaphase • ubiquitin-dependent protein catabolic process • ubiquitin cycle • cell cycle • regulation of mitotic metaphase/anaphase transition • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014885 (mRNA)
NP_055700 (protein)

NM_026904 (mRNA)
NP_081180 (protein)

Location

Chr 4: 146.14 - 146.24 Mb

Chr 8: 82.61 - 82.68 Mb

Pubmed search

[1]

[2]

Anaphase promoting complex subunit 10, also known as ANAPC10, is a human gene.^[1]

[edit] References

^ Entrez Gene: ANAPC10 anaphase promoting complex subunit 10.

[edit] Further reading

Grossberger R, Gieffers C, Zachariae W, et al. (1999). "Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex.". J. Biol. Chem. 274 (20): 14500–7. PMID 10318877.
Kurasawa Y, Todokoro K (1999). "Identification of human APC10/Doc1 as a subunit of anaphase promoting complex.". Oncogene 18 (37): 5131–7. doi:10.1038/sj.onc.1203133. PMID 10498862.
Gotthardt M, Trommsdorff M, Nevitt MF, et al. (2000). "Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.". J. Biol. Chem. 275 (33): 25616–24. doi:10.1074/jbc.M000955200. PMID 10827173.
Gmachl M, Gieffers C, Podtelejnikov AV, et al. (2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.". Proc. Natl. Acad. Sci. U.S.A. 97 (16): 8973–8. PMID 10922056.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Wendt KS, Vodermaier HC, Jacob U, et al. (2001). "Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex.". Nat. Struct. Biol. 8 (9): 784–8. doi:10.1038/nsb0901-784. PMID 11524682.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Vodermaier HC, Gieffers C, Maurer-Stroh S, et al. (2004). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1.". Curr. Biol. 13 (17): 1459–68. PMID 12956947.
Nourry C, Maksumova L, Pang M, et al. (2005). "Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1.". BMC Cell Biol. 5: 20. doi:10.1186/1471-2121-5-20. PMID 15144564.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.