AMP-thymidine kinase

From Wikipedia, the free encyclopedia

In enzymology, an AMP-thymidine kinase (EC 2.7.1.114) is an enzyme that catalyzes the chemical reaction

AMP + thymidine adenosine + thymidine 5'-phosphate

Thus, the two substrates of this enzyme are AMP and thymidine, whereas its two products are adenosine and thymidine 5'-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is AMP:thymidine 5'-phosphotransferase. This enzyme is also called adenylate-nucleoside phosphotransferase.

[edit] References

• IUBMB entry for 2.7.1.114
• BRENDA references for 2.7.1.114 (Recommended.)
• PubMed references for 2.7.1.114
• PubMed Central references for 2.7.1.114
• Google Scholar references for 2.7.1.114
• Falke D, Labenz J, Brauer D, Muller WE (1982). "Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase". Biochim. Biophys. Acta. 708: 99–103. PMID 6293576. 
• Falke D, Nehrbass W, Brauer D, Muller WE (1981). "Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the existence of a novel herpes simplex virus-induced enzyme". J. Gen. Virol. 53: 247–55. PMID 6267178. 

[edit] External links

The CAS registry number for this enzyme class is 60440-28-0.

• IUBMB entry for 2.7.1.114

• KEGG entry for 2.7.1.114

• BRENDA entry for 2.7.1.114

• NiceZyme view of 2.7.1.114

• EC2PDB: PDB structures for 2.7.1.114

• PRIAM entry for 2.7.1.114

• PUMA2 entry for 2.7.1.114

• IntEnz: Integrated Enzyme entry for 2.7.1.114

• MetaCyc entry for 2.7.1.114

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047667: AMP-thymidine kinase

• AMIGO entry for GO code 0047667: AMP-thymidine kinase