Amine sulfotransferase

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In enzymology, an amine sulfotransferase (EC 2.8.2.3) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + an amine adenosine 3',5'-bisphosphate + a sulfamate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and amine, whereas its two products are adenosine 3',5'-bisphosphate and sulfamate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase. Other names in common use include arylamine sulfotransferase, and amine N-sulfotransferase. This enzyme participates in sulfur metabolism.

[edit] References

• IUBMB entry for 2.8.2.3
• BRENDA references for 2.8.2.3 (Recommended.)
• PubMed references for 2.8.2.3
• PubMed Central references for 2.8.2.3
• Google Scholar references for 2.8.2.3
• Ramaswamy SG, Jakoby WB (1987). "Amine N-sulfotransferase". J. Biol. Chem. 262: 10039–43. PMID 3475273. 
• Roy, AB (1960). "The enzymic synthesis of aryl sulphamates". Biochem. J. 74: 49–56. 

[edit] External links

The CAS registry number for this enzyme class is 9026-08-8.

• IUBMB entry for 2.8.2.3

• KEGG entry for 2.8.2.3

• BRENDA entry for 2.8.2.3

• NiceZyme view of 2.8.2.3

• EC2PDB: PDB structures for 2.8.2.3

• PRIAM entry for 2.8.2.3

• PUMA2 entry for 2.8.2.3

• IntEnz: Integrated Enzyme entry for 2.8.2.3

• MetaCyc entry for 2.8.2.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047685: amine sulfotransferase

• AMIGO entry for GO code 0047685: amine sulfotransferase