Alpha-factor-transporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, an alpha-factor-transporting ATPase (EC 3.6.3.48) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + alpha-factorin ADP + phosphate + alpha-factorout

The 3 substrates of this enzyme are ATP, H₂O, and alpha-factor, whereas its 3 products are ADP, phosphate, and alpha-factor.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (alpha-factor-transporting).

[edit] References

• IUBMB entry for 3.6.3.48
• BRENDA references for 3.6.3.48 (Recommended.)
• PubMed references for 3.6.3.48
• PubMed Central references for 3.6.3.48
• Google Scholar references for 3.6.3.48
• Michaelis S (1993). "STE6, the yeast a-factor transporter". Semin. Cell. Biol. 4: 17–27. doi:10.1006/scel.1993.1003. PMID 8095825. 
• Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977. 

[edit] External links

• IUBMB entry for 3.6.3.48

• KEGG entry for 3.6.3.48

• BRENDA entry for 3.6.3.48

• NiceZyme view of 3.6.3.48

• EC2PDB: PDB structures for 3.6.3.48

• PRIAM entry for 3.6.3.48

• PUMA2 entry for 3.6.3.48

• IntEnz: Integrated Enzyme entry for 3.6.3.48

• MetaCyc entry for 3.6.3.48

• Atomic-resolution structures of enzymes belonging to this class