Alloantigen

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Alloantigen can be defined as an antigen that is a part of an animal's self-recognition system. e.g., Major histocompatibility complex molecules. When injected into another animal, they trigger an immune response aimed at eliminating them. Therefore, it can thought of as an antigen that is present in some members of the same species, but is not common to all members of that species. If an alloantigen is presented to a member of the same species that does not have the alloantigen, it will be recognized as foreign. They are the products of polymorphic genes.[1]

One form is known as "Qa-1".[2]

[edit] See also

[edit] References

  1. ^ Abbas AK and Lichtman AH. Basic Immunology: Functions and Disorders of the Immune System. Second Edition, Updated Edition 2006-2007. Elsevier Saunders Publishing.
  2. ^ Germana S, Shinohara N (December 1991). "Qa-1/Tla region alloantigen-specific CTL with alpha beta receptor". Immunology 74 (4): 578–82. PMID 1838350. 

[edit] External links

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