Alkylglycerol kinase

From Wikipedia, the free encyclopedia

In enzymology, an alkylglycerol kinase (EC 2.7.1.93) is an enzyme that catalyzes the chemical reaction

ATP + 1-O-alkyl-sn-glycerol ADP + 1-O-alkyl-sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are ATP and 1-O-alkyl-sn-glycerol, whereas its two products are ADP and 1-O-alkyl-sn-glycerol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase. Other names in common use include 1-alkylglycerol kinase (phosphorylating), ATP-alkylglycerol phosphotransferase, alkylglycerol phosphotransferase, and ATP: 1-alkyl-sn-glycerol phosphotransferase. This enzyme participates in ether lipid metabolism.

[edit] References

• IUBMB entry for 2.7.1.93
• BRENDA references for 2.7.1.93 (Recommended.)
• PubMed references for 2.7.1.93
• PubMed Central references for 2.7.1.93
• Google Scholar references for 2.7.1.93
• Rock CO, Snyder F (1974). "Biosynthesis of 1-alkyl-sn-glycero-3-phosphate via adenosine triphosphate:1-alkyl-sn-glycerol phosphotransferase". J. Biol. Chem. 249: 5382–7. PMID 4369816. 

[edit] External links

The CAS registry number for this enzyme class is 55354-37-5.

• IUBMB entry for 2.7.1.93

• KEGG entry for 2.7.1.93

• BRENDA entry for 2.7.1.93

• NiceZyme view of 2.7.1.93

• EC2PDB: PDB structures for 2.7.1.93

• PRIAM entry for 2.7.1.93

• PUMA2 entry for 2.7.1.93

• IntEnz: Integrated Enzyme entry for 2.7.1.93

• MetaCyc entry for 2.7.1.93

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047649: alkylglycerol kinase

• AMIGO entry for GO code 0047649: alkylglycerol kinase