Alkenylglycerophosphocholine hydrolase

From Wikipedia, the free encyclopedia

In enzymology, an alkenylglycerophosphocholine hydrolase (EC 3.3.2.2) is an enzyme that catalyzes the chemical reaction

1-(1-alkenyl)-sn-glycero-3-phosphocholine + H₂O an aldehyde + sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphocholine and H₂O, whereas its two products are aldehyde and sn-glycero-3-phosphocholine.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase. This enzyme is also called lysoplasmalogenase. This enzyme participates in ether lipid metabolism.

[edit] References

• IUBMB entry for 3.3.2.2
• BRENDA references for 3.3.2.2 (Recommended.)
• PubMed references for 3.3.2.2
• PubMed Central references for 3.3.2.2
• Google Scholar references for 3.3.2.2
• Arthur G, Page L, Mock T, Choy PC (1986). "The catabolism of plasmenylcholine in the guinea pig heart". Biochem. J. 236: 475–80. PMID 3753461. 
• Ellingson JS and Lands WEM (1968). "Phospholipid reactivation of plasmalogen metabolism". Lipids 3: 111–120. doi:10.1007/BF02531727. 
• Warner HR and Lands WEM (1961). "The metabolism of plasmalogen: enzymatic hydrolysis of the vinyl ether". J. Biol. Chem. 236: 2404–2409. 

[edit] External links

The CAS registry number for this enzyme class is 37288-65-6.

• IUBMB entry for 3.3.2.2

• KEGG entry for 3.3.2.2

• BRENDA entry for 3.3.2.2

• NiceZyme view of 3.3.2.2

• EC2PDB: PDB structures for 3.3.2.2

• PRIAM entry for 3.3.2.2

• PUMA2 entry for 3.3.2.2

• IntEnz: Integrated Enzyme entry for 3.3.2.2

• MetaCyc entry for 3.3.2.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047408: alkenylglycerophosphocholine hydrolase

• AMIGO entry for GO code 0047408: alkenylglycerophosphocholine hydrolase