Talk:Aldosterone
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i have too much
- Conn's syndrome? JFW | T@lk 02:24, 10 Mar 2005 (UTC)
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[edit] Renin
Umm, Renin? I gather that the hypothalmus produces Renin which converts angiotensin I to angiotensin II causing the adrenal cortex to release Aldosterone. I came here to confirm that, though, and there's nothing here on that.
- Renin is produced by the kidneys and converts angiotensinogen to angiotensin I. See renin-angiotensin system. --David Iberri 22:12, 16 November 2005 (UTC)
Where is reference to aldosterone and cytokines in hyperthermia? Not in PubMed jftait 15Dec05
Renin is produced in the juxtaglomerular cells of the kidney, usually the juxtaglomerular cells are stimulated by prostacyclin which is released from the macula densa if there is a decrease in urine sodium
[edit] Removed the following paragraph from article
"about 75% of the daily production is secreted between 04:00 am and 10:00 am each day" That is just false. It depends on when you wake up..
[edit] Aldosterone correction
In aldosterone section 'human (corticosterone in rodents)' is not correct. Aldosterone is the dominant mineralocorticoid in all mammals studied. Corticosterone is actually the dominant glucocorticoid in rodents as cortisol the dominant glucocorticoid in humans is not produced in rodents (no 17 hydoxylase). Corticosterone, although slightly more potent than cortisol, is actually quite weak in mineralocorticoid activity. Corticosterone is probably more than 1000 time less potent (per equivalent mass) than aldosterone which is definitely secreted in appreciable amounts by rodents. This sentence gives the wrong iumpression and should be corrected. 'mammals' instead of 'human (corticosterone in rodents' should be sufficient.
James Tait
—The preceding unsigned comment was added by 80.189.140.245 (talk) 19:47, 9 December 2006 (UTC).
[edit] Principal Cells
Are not principle cells in the collecting duct? The article implies that it is in the distal tubule. --Shishidontknwshit

