ADI1

From Wikipedia, the free encyclopedia

Acireductone dioxygenase 1

Identifiers

ADI1; APL1; ARD; FLJ10913; HMFT1638; MTCBP-1; SIPL

External IDs

Gene ontology
Molecular Function:	• protein binding • nickel ion binding • oxidoreductase activity • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen • metal ion binding
Cellular Component:	• nucleus • cytoplasm • plasma membrane
Biological Process:	• amino acid biosynthetic process • methionine biosynthetic process • methionine salvage

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018269 (mRNA)
NP_060739 (protein)

XM_987531 (mRNA)
XP_992625 (protein)

Location

Chr 2: 3.48 - 3.5 Mb

Chr 12: 29.26 - 29.27 Mb

Pubmed search

[1]

[2]

Acireductone dioxygenase 1, also known as ADI1, is a human gene.^[1]

[edit] References

^ Entrez Gene: ADI1 acireductone dioxygenase 1.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Yeh CT, Lai HY, Chen TC, et al. (2001). "Identification of a hepatic factor capable of supporting hepatitis C virus replication in a nonpermissive cell line.". J. Virol. 75 (22): 11017-24. doi:10.1128/JVI.75.22.11017-11024.2001. PMID 11602742.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Uekita T, Gotoh I, Kinoshita T, et al. (2004). "Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.". J. Biol. Chem. 279 (13): 12734-43. doi:10.1074/jbc.M309957200. PMID 14718544.
Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.". Oncogene 23 (35): 5901-11. doi:10.1038/sj.onc.1207782. PMID 15221005.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724-31. doi:10.1038/nature03466. PMID 15815621.
Hirano W, Gotoh I, Uekita T, Seiki M (2005). "Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway.". Genes Cells 10 (6): 565-74. doi:10.1111/j.1365-2443.2005.00859.x. PMID 15938715.
Gotoh I, Uekita T, Seiki M (2007). "Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing.". Genes Cells 12 (1): 105-17. doi:10.1111/j.1365-2443.2006.01035.x. PMID 17212658.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Oram SW, Ai J, Pagani GM, et al. (2007). "Expression and function of the human androgen-responsive gene ADI1 in prostate cancer.". Neoplasia 9 (8): 643-51. PMID 17786183.