ACOT12

From Wikipedia, the free encyclopedia

Acyl-CoA thioesterase 12

Identifiers

ACOT12; CACH-1; Cach; MGC105114; STARD15; THEAL

External IDs

MGI: 1921406 HomoloGene: 12540

Gene ontology
Molecular Function:	• acetyl-CoA hydrolase activity • carboxylesterase activity • ATP binding • hydrolase activity
Cellular Component:	• cytosol
Biological Process:	• acetyl-CoA metabolic process • lipid metabolic process • acyl-CoA metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_130767 (mRNA)
NP_570123 (protein)

NM_028790 (mRNA)
NP_083066 (protein)

Location

Chr 5: 80.66 - 80.73 Mb

Chr 13: 92.22 - 92.26 Mb

Pubmed search

[1]

[2]

Acyl-CoA thioesterase 12, also known as ACOT12, is a human gene.^[1]

[edit] References

^ Entrez Gene: ACOT12 acyl-CoA thioesterase 12.

[edit] Further reading

Suematsu N, Isohashi F (2007). "Molecular cloning and functional expression of human cytosolic acetyl-CoA hydrolase.". Acta Biochim. Pol. 53 (3): 553-61. PMID 16951743.
Hunt MC, Rautanen A, Westin MA, et al. (2006). "Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.". FASEB J. 20 (11): 1855-64. doi:10.1096/fj.06-6042com. PMID 16940157.
Hunt MC, Yamada J, Maltais LJ, et al. (2005). "A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.". J. Lipid Res. 46 (9): 2029-32. doi:10.1194/jlr.E500003-JLR200. PMID 16103133.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Suematsu N, Okamoto K, Isohashi F (2004). "Simple and unique purification by size-exclusion chromatography for an oligomeric enzyme, rat liver cytosolic acetyl-coenzyme A hydrolase.". J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 790 (1-2): 239-44. PMID 12767336.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Suematsu N, Okamoto K, Shibata K, et al. (2001). "Molecular cloning and functional expression of rat liver cytosolic acetyl-CoA hydrolase.". Eur. J. Biochem. 268 (9): 2700-9. PMID 11322891.