Acetyllysine
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| Acetyllysine[1] | |
|---|---|
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| IUPAC name | (2S)-6-Acetamido-2-aminohexanoic acid |
| Other names | 6-N-Acetyllysine Nε-Acetyl-L-lysine |
| Identifiers | |
| CAS number | [692-04-6] |
| PubChem | |
| SMILES | CC(=O)NCCCCC(C(=O)O)N |
| Properties | |
| Molecular formula | C8H16N2O3 |
| Molar mass | 188.22 g/mol |
| Melting point |
250 °C (dec.) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Acetyllysine is an acetyl-derivative of the amino acid lysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
[edit] References
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