Acetylenedicarboxylate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, an acetylenedicarboxylate decarboxylase (EC 4.1.1.78) is an enzyme that catalyzes the chemical reaction

acetylenedicarboxylate + H₂O pyruvate + CO₂

Thus, the two substrates of this enzyme are acetylenedicarboxylate and H₂O, whereas its two products are pyruvate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.

[edit] References

• IUBMB entry for 4.1.1.78
• BRENDA references for 4.1.1.78 (Recommended.)
• PubMed references for 4.1.1.78
• PubMed Central references for 4.1.1.78
• Google Scholar references for 4.1.1.78
• Yamada EW and Jakoby WB (1958). "Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate". J. Biol. Chem. 233: 706–711. 

[edit] External links

The CAS registry number for this enzyme class is 72561-10-5.

• IUBMB entry for 4.1.1.78

• KEGG entry for 4.1.1.78

• BRENDA entry for 4.1.1.78

• NiceZyme view of 4.1.1.78

• EC2PDB: PDB structures for 4.1.1.78

• PRIAM entry for 4.1.1.78

• PUMA2 entry for 4.1.1.78

• IntEnz: Integrated Enzyme entry for 4.1.1.78

• MetaCyc entry for 4.1.1.78

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050476: acetylenedicarboxylate decarboxylase

• AMIGO entry for GO code 0050476: acetylenedicarboxylate decarboxylase