Abequosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an abequosyltransferase (EC 2.4.1.60) is an enzyme that catalyzes the chemical reaction

CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid

Thus, the two substrates of this enzyme are CDP-abequose and D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid, whereas its two products are CDP and D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase. This enzyme is also called trihexose diphospholipid abequosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.60
• BRENDA references for 2.4.1.60 (Recommended.)
• PubMed references for 2.4.1.60
• PubMed Central references for 2.4.1.60
• Google Scholar references for 2.4.1.60
• Osborn MJ, Weiner IM (1968). "Biosynthesis of a bacterial lipopolysaccharide. VI. Mechanism of incorporation of abequose into the O-antigen of Salmonella typhimurium". J. Biol. Chem. 243: 2631–9. PMID 4297268. 

[edit] External links

The CAS registry number for this enzyme class is 37277-67-1.

• IUBMB entry for 2.4.1.60

• KEGG entry for 2.4.1.60

• BRENDA entry for 2.4.1.60

• NiceZyme view of 2.4.1.60

• EC2PDB: PDB structures for 2.4.1.60

• PRIAM entry for 2.4.1.60

• PUMA2 entry for 2.4.1.60

• IntEnz: Integrated Enzyme entry for 2.4.1.60

• MetaCyc entry for 2.4.1.60

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047600: abequosyltransferase

• AMIGO entry for GO code 0047600: abequosyltransferase