6-aminohexanoate-dimer hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a 6-aminohexanoate-dimer hydrolase (EC 3.5.1.46) is an enzyme that catalyzes the chemical reaction

N-(6-aminohexanoyl)-6-aminohexanoate + H₂O 2 6-aminohexanoate

Thus, the two substrates of this enzyme are N-(6-aminohexanoyl)-6-aminohexanoate and H₂O, whereas its product is 6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase. This enzyme is also called 6-aminohexanoic acid oligomer hydrolase.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1WYB, 1WYC, and 2DCF.

[edit] References

• IUBMB entry for 3.5.1.46
• BRENDA references for 3.5.1.46 (Recommended.)
• PubMed references for 3.5.1.46
• PubMed Central references for 3.5.1.46
• Google Scholar references for 3.5.1.46
• Okada H (1981). "Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72". Eur. J. Biochem. 116: 547–51. doi:10.1111/j.1432-1033.1981.tb05371.x. PMID 7262074. 

[edit] External links

The CAS registry number for this enzyme class is 75216-15-8.

• IUBMB entry for 3.5.1.46

• KEGG entry for 3.5.1.46

• BRENDA entry for 3.5.1.46

• NiceZyme view of 3.5.1.46

• EC2PDB: PDB structures for 3.5.1.46

• PRIAM entry for 3.5.1.46

• PUMA2 entry for 3.5.1.46

• IntEnz: Integrated Enzyme entry for 3.5.1.46

• MetaCyc entry for 3.5.1.46

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019875: 6-aminohexanoate-dimer hydrolase

• AMIGO entry for GO code 0019875: 6-aminohexanoate-dimer hydrolase