Talk:5-HT receptor

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More references needed throughout. -- MarcoTolo 01:27, 6 March 2007 (UTC)

Gepiron and ipsapiron are also 5HT1A receptor activators

I replaced "mirtazepine" for "mirtazapine", which is a more common spelling and has an article under it. - Ktai 08:56, 15 October 2006 (UTC)

Contents

[edit] Linking to this page

I've seen many pages with references to various 5-HT receptors, particularly in the pharmaceutical and hallucinogenic substance area since that is the area i most frequent, and rarely do i come upon links to this page. In fact i have just discovered this article. I think it'd be appropriate to work on adding this page as a link to the articles in which the references to 5-HT*'s are not linked to anything, so if one might see this i urge you to add the page as a link.--Neur0X .talk 04:59, 25 December 2006 (UTC)

[edit] or possibly just merge the page

its is quite a large page already so it might be better off separated. If some one was to write separate articles for the sub categories of 5-HT then it could be left alone and linked to as a sub category —The preceding unsigned comment was added by 195.137.90.137 (talk) 14:00, 7 March 2007 (UTC).

[edit] LSD as a 5-HT2A agonist AND antagonist?

Hey,

I believe there's been an error. LSD is listed as a 5-HT2A agonist and antagonist, both. This should be impossible, but I'm wary about changing the article without an actual chemist's say on it. (I believe it should be agonist only.) 68.19.27.176 05:16, 16 September 2007 (UTC)

  • You are correct as documented here. LSD is a 5-HT2A agonist whose effects can be blocked by 5-HT2A antagonists. I have therefore removed LSD from the 5-HT2A antagonist list. Boghog2 08:02, 16 September 2007 (UTC)
  • After more careful reading of the article, LSD is listed as an agonist in the CNS and antagonist in the peripheral nervous system which is possible. There are early reports that LSD acts as antagonist in peripheral tissues [Gaddum JH (1953). "Antagonism between lysergic acid diethylamide and 5-hydroxytryptamine". J. Physiol. (Lond.) 121 (1): 15P. PMID 13085323. ], but I cannot find any references specifically mentioning that LSD is a peripheral 5-HT2A antagonist. So I will leave the list as is for now. Boghog2 08:38, 16 September 2007 (UTC)

[edit] RUBBISH

Some receptors increase cAMP

type 4, 6 and 7 for example —Preceding unsigned comment added by 129.215.149.98 (talk) 12:53, 8 November 2007 (UTC)

[edit] 5-HT5 Receptor

Article lists as Gi-coupled, my sources say it's Gs-coupled. This should be confirmed. Snellios (talk) 10:18, 28 April 2008 (UTC)