5-hydroxypentanoate CoA-transferase

From Wikipedia, the free encyclopedia

In enzymology, a 5-hydroxypentanoate CoA-transferase (EC 2.8.3.14) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + 5-hydroxypentanoate acetate + 5-hydroxypentanoyl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and 5-hydroxypentanoate, whereas its two products are acetate and 5-hydroxypentanoyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:5-hydroxypentanoate CoA-transferase. Other names in common use include 5-hydroxyvalerate CoA-transferase, and 5-hydroxyvalerate coenzyme A transferase.

[edit] References

• IUBMB entry for 2.8.3.14
• BRENDA references for 2.8.3.14 (Recommended.)
• PubMed references for 2.8.3.14
• PubMed Central references for 2.8.3.14
• Google Scholar references for 2.8.3.14
• Eikmanns U, Buckel W (1990). "Properties of 5-hydroxyvalerate CoA-transferase from Clostridium aminovalericum". Biol. Chem. Hoppe. Seyler. 371: 1077–82. PMID 2085413. 

[edit] External links

The CAS registry number for this enzyme class is 111684-68-5.

• IUBMB entry for 2.8.3.14

• KEGG entry for 2.8.3.14

• BRENDA entry for 2.8.3.14

• NiceZyme view of 2.8.3.14

• EC2PDB: PDB structures for 2.8.3.14

• PRIAM entry for 2.8.3.14

• PUMA2 entry for 2.8.3.14

• IntEnz: Integrated Enzyme entry for 2.8.3.14

• MetaCyc entry for 2.8.3.14

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047591: 5-hydroxypentanoate CoA-transferase

• AMIGO entry for GO code 0047591: 5-hydroxypentanoate CoA-transferase