4-pyridoxolactonase

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In enzymology, a 4-pyridoxolactonase (EC 3.1.1.27) is an enzyme that catalyzes the chemical reaction

4-pyridoxolactone + H₂O 4-pyridoxate

Thus, the two substrates of this enzyme are 4-pyridoxolactone and H₂O, whereas its product is 4-pyridoxate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 4-pyridoxolactone lactonohydrolase. This enzyme participates in vitamin b6 metabolism.

[edit] References

• IUBMB entry for 3.1.1.27
• BRENDA references for 3.1.1.27 (Recommended.)
• PubMed references for 3.1.1.27
• PubMed Central references for 3.1.1.27
• Google Scholar references for 3.1.1.27
• Burg RW, Snell EE (1969). "The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244: 2585–9. PMID 4306030. 

[edit] External links

The CAS registry number for this enzyme class is 37278-41-4.

• IUBMB entry for 3.1.1.27

• KEGG entry for 3.1.1.27

• BRENDA entry for 3.1.1.27

• NiceZyme view of 3.1.1.27

• EC2PDB: PDB structures for 3.1.1.27

• PRIAM entry for 3.1.1.27

• PUMA2 entry for 3.1.1.27

• IntEnz: Integrated Enzyme entry for 3.1.1.27

• MetaCyc entry for 3.1.1.27

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047585: 4-pyridoxolactonase

• AMIGO entry for GO code 0047585: 4-pyridoxolactonase