4-oxalocrotonate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a 4-oxalocrotonate decarboxylase (EC 4.1.1.77) is an enzyme that catalyzes the chemical reaction

4-oxalocrotonate 2-oxopent-4-enoate + CO₂

Hence, this enzyme has one substrate, 4-oxalocrotonate, and two products, 2-oxopent-4-enoate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming). This enzyme is also called 4-oxalocrotonate carboxy-lyase. This enzyme participates in 3 metabolic pathways: benzoate degradation via hydroxylation, toluene and xylene degradation, and fluorene degradation.

[edit] References

• IUBMB entry for 4.1.1.77
• BRENDA references for 4.1.1.77 (Recommended.)
• PubMed references for 4.1.1.77
• PubMed Central references for 4.1.1.77
• Google Scholar references for 4.1.1.77
• Shingler V, Powlowski J, Marklund U (1992). "Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp strain CF600". J. Bacteriol. 174: 711–24. PMID 1732207. 

[edit] External links

The CAS registry number for this enzyme class is 37325-55-6.

• IUBMB entry for 4.1.1.77

• KEGG entry for 4.1.1.77

• BRENDA entry for 4.1.1.77

• NiceZyme view of 4.1.1.77

• EC2PDB: PDB structures for 4.1.1.77

• PRIAM entry for 4.1.1.77

• PUMA2 entry for 4.1.1.77

• IntEnz: Integrated Enzyme entry for 4.1.1.77

• MetaCyc entry for 4.1.1.77

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047437: 4-oxalocrotonate decarboxylase

• AMIGO entry for GO code 0047437: 4-oxalocrotonate decarboxylase