4-nitrophenylphosphatase

From Wikipedia, the free encyclopedia

In enzymology, a 4-nitrophenylphosphatase (EC 3.1.3.41) is an enzyme that catalyzes the chemical reaction

4-nitrophenyl phosphate + H₂O $\rightleftharpoons$ 4-nitrophenol + phosphate

Thus, the two substrates of this enzyme are 4-nitrophenyl phosphate and H₂O, whereas its two products are 4-nitrophenol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 4-nitrophenylphosphate phosphohydrolase. Other names in common use include nitrophenyl phosphatase, p-nitrophenylphosphatase, para-nitrophenyl phosphatase, K-pNPPase, NPPase, PNPPase, Ecto-p-nitrophenyl phosphatase, and p-nitrophenylphosphate phosphohydrolase. This enzyme participates in gamma-hexachlorocyclohexane degradation.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1VJR.

[edit] References

IUBMB entry for 3.1.3.41
BRENDA references for 3.1.3.41 (Recommended.)
PubMed references for 3.1.3.41
PubMed Central references for 3.1.3.41
Google Scholar references for 3.1.3.41
Attias J, Bonnet JL (1972). "A specific alkaline p-nitrophenylphosphatase activity from baker's yeast". Biochim. Biophys. Acta. 268: 422–30. PMID 4554643.
Attias J, Durand H (1973). "Further characterization of a specific p-nitrophenylphosphatase from baker's yeast". Biochim. Biophys. Acta. 321: 561–8. PMID 4357666.