4-hydroxyphenylpyruvate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a 4-hydroxyphenylpyruvate decarboxylase (EC 4.1.1.80) is an enzyme that catalyzes the chemical reaction

4-hydroxyphenylpyruvate 4-hydroxyphenylacetaldehyde + CO₂

Hence, this enzyme has one substrate, 4-hydroxyphenylpyruvate, and two products, 4-hydroxyphenylacetaldehyde and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming). This enzyme is also called 4-hydroxyphenylpyruvate carboxy-lyase.

[edit] References

• IUBMB entry for 4.1.1.80
• BRENDA references for 4.1.1.80 (Recommended.)
• PubMed references for 4.1.1.80
• PubMed Central references for 4.1.1.80
• Google Scholar references for 4.1.1.80
• Rueffer M and Zenk MH (1987). "Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation". Z. Naturforsch. C: Biosci. 42: 319–332. 

[edit] External links

The CAS registry number for this enzyme class is 109300-96-1.

• IUBMB entry for 4.1.1.80

• KEGG entry for 4.1.1.80

• BRENDA entry for 4.1.1.80

• NiceZyme view of 4.1.1.80

• EC2PDB: PDB structures for 4.1.1.80

• PRIAM entry for 4.1.1.80

• PUMA2 entry for 4.1.1.80

• IntEnz: Integrated Enzyme entry for 4.1.1.80

• MetaCyc entry for 4.1.1.80

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050546: 4-hydroxyphenylpyruvate decarboxylase

• AMIGO entry for GO code 0050546: 4-hydroxyphenylpyruvate decarboxylase