3F8
From Wikipedia, the free encyclopedia
3F8 is a murine, IgG3[1] monoclonal antibody which binds to GD2.[2]
It has been used in the detection and treatment of neuroblastoma.[3]<[4][5]
[edit] See also
[edit] References
- ^ Kushner BH, Cheung NK (1989). "GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma". Blood 73 (7): 1936–41. PMID 2653466.
- ^ Sloan-Kettering - Neuroblastoma: 3F8 Monoclonal Antibody Therapy Q & A. Retrieved on 2008-02-19.
- ^ ACS :: New Drug Targets Tough
Childhood Cancer. Retrieved on 2008-02-19. - ^ Yeh SD, Larson SM, Burch L, et al (1991). "Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities". J. Nucl. Med. 32 (5): 769–76. PMID 1902508.
- ^ Dauer LT, St Germain J, Williamson MJ, et al (2007). "Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma". Health Phys 92 (1): 33–9. doi:. PMID 17164597.
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