3-deoxy-manno-octulosonate-8-phosphatase

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In enzymology, a 3-deoxy-manno-octulosonate-8-phosphatase (EC 3.1.3.45) is an enzyme that catalyzes the chemical reaction

3-deoxy-D-manno-octulosonate 8-phosphate + H₂O 3-deoxy-D-manno-octulosonate + phosphate

Thus, the two substrates of this enzyme are 3-deoxy-D-manno-octulosonate 8-phosphate and H₂O, whereas its two products are 3-deoxy-D-manno-octulosonate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase. This enzyme participates in lipopolysaccharide biosynthesis.

[edit] References

• IUBMB entry for 3.1.3.45
• BRENDA references for 3.1.3.45 (Recommended.)
• PubMed references for 3.1.3.45
• PubMed Central references for 3.1.3.45
• Google Scholar references for 3.1.3.45
• Ray PH, Benedict CD (1980). "Purification and characterization of specific 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase from Escherichia coli B". J. Bacteriol. 142: 60–8. PMID 6246070. 

[edit] External links

The CAS registry number for this enzyme class is 59088-24-3.

• IUBMB entry for 3.1.3.45

• KEGG entry for 3.1.3.45

• BRENDA entry for 3.1.3.45

• NiceZyme view of 3.1.3.45

• EC2PDB: PDB structures for 3.1.3.45

• PRIAM entry for 3.1.3.45

• PUMA2 entry for 3.1.3.45

• IntEnz: Integrated Enzyme entry for 3.1.3.45

• MetaCyc entry for 3.1.3.45

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0019143: 3-deoxy-manno-octulosonate-8-phosphatase

• AMIGO entry for GO code 0019143: 3-deoxy-manno-octulosonate-8-phosphatase