24-methylenesterol C-methyltransferase

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In enzymology, a 24-methylenesterol C-methyltransferase (EC 2.1.1.143) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 24-methylenelophenol S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol

Thus, the two substrates of this enzyme are S-adenosyl methionine and 24-methylenelophenol, whereas its two products are S-adenosylhomocysteine and (Z)-24-ethylidenelophenol.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase. Other names in common use include SMT2, and 24-methylenelophenol C-241-methyltransferase. This enzyme participates in the biosynthesis of steroids.

[edit] References

• IUBMB entry for 2.1.1.143
• BRENDA references for 2.1.1.143 (Recommended.)
• PubMed references for 2.1.1.143
• PubMed Central references for 2.1.1.143
• Google Scholar references for 2.1.1.143
• Bouvier-Nave P, Husselstein T, Benveniste P (1998). "Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis". Eur. J. Biochem. 256: 88–96. doi:10.1046/j.1432-1327.1998.2560088.x. PMID 9746350. 

[edit] External links

• IUBMB entry for 2.1.1.143

• KEGG entry for 2.1.1.143

• BRENDA entry for 2.1.1.143

• NiceZyme view of 2.1.1.143

• EC2PDB: PDB structures for 2.1.1.143

• PRIAM entry for 2.1.1.143

• PUMA2 entry for 2.1.1.143

• IntEnz: Integrated Enzyme entry for 2.1.1.143

• MetaCyc entry for 2.1.1.143

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030797: 24-methylenesterol C-methyltransferase

• AMIGO entry for GO code 0030797: 24-methylenesterol C-methyltransferase