2-acylglycerol O-acyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a 2-acylglycerol O-acyltransferase (EC 2.3.1.22) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 2-acylglycerol CoA + diacylglycerol

Thus, the two substrates of this enzyme are acyl-CoA and 2-acylglycerol, whereas its two products are CoA and diacylglycerol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:2-acylglycerol O-acyltransferase. Other names in common use include acylglycerol palmitoyltransferase, monoglyceride acyltransferase, acyl coenzyme A-monoglyceride acyltransferase, and monoacylglycerol acyltransferase. This enzyme participates in glycerolipid metabolism.

[edit] References

• IUBMB entry for 2.3.1.22
• BRENDA references for 2.3.1.22 (Recommended.)
• PubMed references for 2.3.1.22
• PubMed Central references for 2.3.1.22
• Google Scholar references for 2.3.1.22
• Manganaro F, Kuksis A (1985). "Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells". Can. J. Biochem. Cell. Biol. 63: 341–7. PMID 4016575. 

[edit] External links

The CAS registry number for this enzyme class is 9055-17-8.

• IUBMB entry for 2.3.1.22

• KEGG entry for 2.3.1.22

• BRENDA entry for 2.3.1.22

• NiceZyme view of 2.3.1.22

• EC2PDB: PDB structures for 2.3.1.22

• PRIAM entry for 2.3.1.22

• PUMA2 entry for 2.3.1.22

• IntEnz: Integrated Enzyme entry for 2.3.1.22

• MetaCyc entry for 2.3.1.22

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0003846: 2-acylglycerol O-acyltransferase

• AMIGO entry for GO code 0003846: 2-acylglycerol O-acyltransferase