2,6-Dimethylpiperidine
From Wikipedia, the free encyclopedia
| 2,6-Dimethylpiperidine | |
|---|---|
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| IUPAC name | 2,6-Dimethylpiperidine |
| Other names | 2,6-Lupetidine |
| Identifiers | |
| CAS number | [766-17-6] |
| RTECS number | OK5775000 |
| SMILES | CC1CCCC(C)N1 |
| Properties | |
| Molecular formula | C7H15N |
| Molar mass | 113.20 g/mol |
| Appearance | Colorless liquid |
| Density | 0.84 g/mL |
| Boiling point |
113.2 |
| Solubility in water | Low |
| Solubility in other solvents | Most organic solvents |
| Basicity (pKb) | ca. 10 |
| Refractive index (nD) | 1.4394 |
| Hazards | |
| Main hazards | Flammable |
| R-phrases | 11-36/37/38 |
| S-phrases | 16-26 |
| Flash point | 53 °F |
| Related compounds | |
| Related compounds | Piperidine |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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2,6-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Two diastereomers exist: the achiral R,S isomer and the chiral R,R/S,S pair. Dimethylpiperidines are derivatives of the heterocycle piperidine, wherein two hydrogen atoms are replaced by methyl groups.
The 2,6-dimethylpiperidines are prepared by reduction of 2,6-dimethylpyridine (2,6-lutidine). The R,S isomer is favored.
The 2,6-dimethylpiperidines are of interest for their conformational properties. The R,S isomer exists largely in the chair conformation with equatorial methyl groups. The R,R/S,S isomers are attractive chiral secondary amine building blocks.[1]
