2,5-diaminovalerate transaminase

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In enzymology, a 2,5-diaminovalerate transaminase (EC 2.6.1.8) is an enzyme that catalyzes the chemical reaction

2,5-diaminopentanoate + 2-oxoglutarate 5-amino-2-oxopentanoate + L-glutamate

Thus, the two substrates of this enzyme are 2,5-diaminopentanoate and 2-oxoglutarate, whereas its two products are 5-amino-2-oxopentanoate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 2,5-diaminopentanoate:2-oxoglutarate aminotransferase. Other names in common use include diamino-acid transaminase, and diamino acid aminotransferase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.6.1.8
• BRENDA references for 2.6.1.8 (Recommended.)
• PubMed references for 2.6.1.8
• PubMed Central references for 2.6.1.8
• Google Scholar references for 2.6.1.8
• ROBERTS E (1954). "Studies of transamination". Arch. Biochem. Biophys. 48: 395–401. doi:10.1016/0003-9861(54)90355-0. PMID 13125615. 

[edit] External links

The CAS registry number for this enzyme class is 9030-39-1.

• IUBMB entry for 2.6.1.8

• KEGG entry for 2.6.1.8

• BRENDA entry for 2.6.1.8

• NiceZyme view of 2.6.1.8

• EC2PDB: PDB structures for 2.6.1.8

• PRIAM entry for 2.6.1.8

• PUMA2 entry for 2.6.1.8

• IntEnz: Integrated Enzyme entry for 2.6.1.8

• MetaCyc entry for 2.6.1.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047531: 2,5-diaminovalerate transaminase

• AMIGO entry for GO code 0047531: 2,5-diaminovalerate transaminase