16-alpha-hydroxyprogesterone dehydratase

From Wikipedia, the free encyclopedia

In enzymology, a 16alpha-hydroxyprogesterone dehydratase (EC 4.2.1.98) is an enzyme that catalyzes the chemical reaction

16alpha-hydroxyprogesterone 16,17-didehydroprogesterone + H₂O

Hence, this enzyme has one substrate, 16alpha-hydroxyprogesterone, and two products, 16,17-didehydroprogesterone and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming). Other names in common use include hydroxyprogesterone dehydroxylase, 16alpha-hydroxyprogesterone dehydroxylase, 16alpha-dehydroxylase, and 16alpha-hydroxyprogesterone hydro-lyase.

[edit] References

• IUBMB entry for 4.2.1.98
• BRENDA references for 4.2.1.98 (Recommended.)
• PubMed references for 4.2.1.98
• PubMed Central references for 4.2.1.98
• Google Scholar references for 4.2.1.98
• Glass TL, Lamppa RS (1985). "Purification and properties of 16 alpha-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144". Biochim. Biophys. Acta. 837: 103–10. PMID 4052439. 

[edit] External links

• IUBMB entry for 4.2.1.98

• KEGG entry for 4.2.1.98

• BRENDA entry for 4.2.1.98

• NiceZyme view of 4.2.1.98

• EC2PDB: PDB structures for 4.2.1.98

• PRIAM entry for 4.2.1.98

• PUMA2 entry for 4.2.1.98

• IntEnz: Integrated Enzyme entry for 4.2.1.98

• MetaCyc entry for 4.2.1.98

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047455: 16-alpha-hydroxyprogesterone dehydratase

• AMIGO entry for GO code 0047455: 16-alpha-hydroxyprogesterone dehydratase