12-hydroxydihydrochelirubine 12-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a 12-hydroxydihydrochelirubine 12-O-methyltransferase (EC 2.1.1.120) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine S-adenosyl-L-homocysteine + dihydromacarpine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 12-hydroxydihydrochelirubine, whereas its two products are S-adenosylhomocysteine and dihydromacarpine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 2.1.1.120
• BRENDA references for 2.1.1.120 (Recommended.)
• PubMed references for 2.1.1.120
• PubMed Central references for 2.1.1.120
• Google Scholar references for 2.1.1.120
• Kammerer L, De-Eknamkul W and Zenk MH (1994). "Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum". Phytochemistry 36: 1409–1416. doi:10.1016/S0031-9422(00)89732-0. 

[edit] External links

The CAS registry number for this enzyme class is 158736-40-4.

• IUBMB entry for 2.1.1.120

• KEGG entry for 2.1.1.120

• BRENDA entry for 2.1.1.120

• NiceZyme view of 2.1.1.120

• EC2PDB: PDB structures for 2.1.1.120

• PRIAM entry for 2.1.1.120

• PUMA2 entry for 2.1.1.120

• IntEnz: Integrated Enzyme entry for 2.1.1.120

• MetaCyc entry for 2.1.1.120

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030780: 12-hydroxydihydrochelirubine 12-O-methyltransferase

• AMIGO entry for GO code 0030780: 12-hydroxydihydrochelirubine 12-O-methyltransferase