10-hydroxydihydrosanguinarine 10-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a 10-hydroxydihydrosanguinarine 10-O-methyltransferase (EC 2.1.1.119) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine S-adenosyl-L-homocysteine + dihydrochelirubine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 10-hydroxydihydrosanguinarine, whereas its two products are S-adenosylhomocysteine and dihydrochelirubine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 2.1.1.119
• BRENDA references for 2.1.1.119 (Recommended.)
• PubMed references for 2.1.1.119
• PubMed Central references for 2.1.1.119
• Google Scholar references for 2.1.1.119
• De-Eknamkul W, Tanahashi T and Zenk MH (1992). "Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia". Phytochemistry 31: 2713–2717. doi:10.1016/0031-9422(92)83617-8. 

[edit] External links

The CAS registry number for this enzyme class is 144388-39-6.

• IUBMB entry for 2.1.1.119

• KEGG entry for 2.1.1.119

• BRENDA entry for 2.1.1.119

• NiceZyme view of 2.1.1.119

• EC2PDB: PDB structures for 2.1.1.119

• PRIAM entry for 2.1.1.119

• PUMA2 entry for 2.1.1.119

• IntEnz: Integrated Enzyme entry for 2.1.1.119

• MetaCyc entry for 2.1.1.119

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030779: 10-hydroxydihydrosanguinarine 10-O-methyltransferase

• AMIGO entry for GO code 0030779: 10-hydroxydihydrosanguinarine 10-O-methyltransferase