1,6-alpha-L-fucosidase

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In enzymology, a 1,6-alpha-L-fucosidase (EC 3.2.1.127) is an enzyme that catalyzes the chemical reaction

Hydrolysis of 1,6-linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. This enzyme is also called alpha-L-fucosidase.

[edit] References

• IUBMB entry for 3.2.1.127
• BRENDA references for 3.2.1.127 (Recommended.)
• PubMed references for 3.2.1.127
• PubMed Central references for 3.2.1.127
• Google Scholar references for 3.2.1.127
• Yazawa S, Madiyalakan R, Chawda RP, Matta KL (1986). "alpha-L-fucosidase from aspergillus niger: demonstration of a novel alpha-L-(1----6)-fucosidase acting on glycopeptides". Biochem. Biophys. Res. Commun. 136: 563–9. doi:10.1016/0006-291X(86)90477-8. PMID 2423086. 

[edit] External links

The CAS registry number for this enzyme class is 102925-35-9.

• IUBMB entry for 3.2.1.127

• KEGG entry for 3.2.1.127

• BRENDA entry for 3.2.1.127

• NiceZyme view of 3.2.1.127

• EC2PDB: PDB structures for 3.2.1.127

• PRIAM entry for 3.2.1.127

• PUMA2 entry for 3.2.1.127

• IntEnz: Integrated Enzyme entry for 3.2.1.127

• MetaCyc entry for 3.2.1.127

• Atomic-resolution structures of enzymes belonging to this class