(S)-scoulerine 9-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a (S)-scoulerine 9-O-methyltransferase (EC 2.1.1.117) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + (S)-scoulerine S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine

Thus, the two substrates of this enzyme are S-adenosyl methionine and (S)-scoulerine, whereas its two products are S-adenosylhomocysteine and (S)-tetrahydrocolumbamine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

[edit] References

• IUBMB entry for 2.1.1.117
• BRENDA references for 2.1.1.117 (Recommended.)
• PubMed references for 2.1.1.117
• PubMed Central references for 2.1.1.117
• Google Scholar references for 2.1.1.117
• Muemmler S, Rueffer M, Nagakura N, Zenk MH (1985). "S-Adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase, a highly stereo- and regiospecific enzyme in tetrahydroberberine biosynthesis". Plant Cell Reports 4: 36–39. doi:10.1007/BF00285501. 

[edit] External links

• IUBMB entry for 2.1.1.117

• KEGG entry for 2.1.1.117

• BRENDA entry for 2.1.1.117

• NiceZyme view of 2.1.1.117

• EC2PDB: PDB structures for 2.1.1.117

• PRIAM entry for 2.1.1.117

• PUMA2 entry for 2.1.1.117

• IntEnz: Integrated Enzyme entry for 2.1.1.117

• MetaCyc entry for 2.1.1.117

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030777: (S)-scoulerine 9-O-methyltransferase

• AMIGO entry for GO code 0030777: (S)-scoulerine 9-O-methyltransferase