Succinyl-CoA:(R)-benzylsuccinate CoA-transferase

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In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + (R)-2-benzylsuccinate $\rightleftharpoons$ succinate + (R)-2-benzylsuccinyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and (R)-2-benzylsuccinate, whereas its two products are succinate and (R)-2-benzylsuccinyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase. This enzyme is also called benzylsuccinate CoA-transferase. This enzyme participates in benzoate degradation via coa ligation.

[edit] References

IUBMB entry for 2.8.3.15
BRENDA references for 2.8.3.15 (Recommended.)
PubMed references for 2.8.3.15
PubMed Central references for 2.8.3.15
Google Scholar references for 2.8.3.15
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Leutwein C, Heider J (Pt 11). "Anaerobic toluene-catabolic pathway in denitrifying Thauera aromatica: activation and beta-oxidation of the first intermediate, (R)-(+)-benzylsuccinate". Microbiology. 145: 3265–71. PMID 10589736.
Leuthner B, Heider J (2000). "Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate". J. Bacteriol. 182: 272–7. PMID 10629170.
Heider J (2001). "A new family of CoA-transferases". FEBS. Lett. 509: 345–9. PMID 11749953.