(myelin-proteolipid) O-palmitoyltransferase

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In enzymology, a [myelin-proteolipid] O-palmitoyltransferase (EC 2.3.1.100) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + [myelin proteolipid] CoA + O-palmitoyl-[myelin proteolipid]

Thus, the two substrates of this enzyme are palmitoyl-CoA and myelin proteolipid, whereas its two products are CoA and O-palmitoyl-myelin proteolipid.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase. Other names in common use include myelin PLP acyltransferase, acyl-protein synthetase, and myelin-proteolipid O-palmitoyltransferase.

[edit] References

• IUBMB entry for 2.3.1.100
• BRENDA references for 2.3.1.100 (Recommended.)
• PubMed references for 2.3.1.100
• PubMed Central references for 2.3.1.100
• Google Scholar references for 2.3.1.100
• Bizzozero OA, McGarry JF, Lees MB (1987). "Acylation of endogenous myelin proteolipid protein with different acyl-CoAs". J. Biol. Chem. 262: 2138–45. PMID 3818589. 

[edit] External links

The CAS registry number for this enzyme class is 82657-98-5.

• IUBMB entry for 2.3.1.100

• KEGG entry for 2.3.1.100

• BRENDA entry for 2.3.1.100

• NiceZyme view of 2.3.1.100

• EC2PDB: PDB structures for 2.3.1.100

• PRIAM entry for 2.3.1.100

• PUMA2 entry for 2.3.1.100

• IntEnz: Integrated Enzyme entry for 2.3.1.100

• MetaCyc entry for 2.3.1.100

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047157: myelin-proteolipid O-palmitoyltransferase

• AMIGO entry for GO code 0047157: myelin-proteolipid O-palmitoyltransferase