(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

From Wikipedia, the free encyclopedia

In enzymology, a (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) is an enzyme that catalyzes the chemical reaction

(1-hydroxycyclohexan-1-yl)acetyl-CoA acetyl-CoA + cyclohexanone

Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.

[edit] References

• IUBMB entry for 4.1.3.35
• BRENDA references for 4.1.3.35 (Recommended.)
• PubMed references for 4.1.3.35
• PubMed Central references for 4.1.3.35
• Google Scholar references for 4.1.3.35
• Ougham HJ, Trudgill PW (1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". J. Bacteriol. 150: 1172–82. PMID 7076617. 

[edit] External links

The CAS registry number for this enzyme class is 71343-09-4.

• IUBMB entry for 4.1.3.35

• KEGG entry for 4.1.3.35

• BRENDA entry for 4.1.3.35

• NiceZyme view of 4.1.3.35

• EC2PDB: PDB structures for 4.1.3.35

• PRIAM entry for 4.1.3.35

• PUMA2 entry for 4.1.3.35

• IntEnz: Integrated Enzyme entry for 4.1.3.35

• MetaCyc entry for 4.1.3.35

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047446: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

• AMIGO entry for GO code 0047446: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase