Ornithine(lysine) transaminase

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In enzymology, an ornithine(lysine) transaminase (EC 2.6.1.68) is an enzyme that catalyzes the chemical reaction

L-ornithine + 2-oxoglutarate 3,4-dihydro-2H-pyrrole-2-carboxylate + L-glutamate + H₂O

Thus, the two substrates of this enzyme are L-ornithine and 2-oxoglutarate, whereas its 3 products are 3,4-dihydro-2H-pyrrole-2-carboxylate, L-glutamate, and H₂O.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-ornithine:2-oxoglutarate-aminotransferase. Other names in common use include ornithine(lysine) aminotransferase, lysine/ornithine:2-oxoglutarate aminotransferase, and L-ornithine(L-lysine):2-oxoglutarate-aminotransferase.

[edit] References

• IUBMB entry for 2.6.1.68
• BRENDA references for 2.6.1.68 (Recommended.)
• PubMed references for 2.6.1.68
• PubMed Central references for 2.6.1.68
• Google Scholar references for 2.6.1.68
• Lowe PN, Rowe AF (1986). "Aminotransferase activities in Trichomonas vaginalis". Mol. Biochem. Parasitol. 21: 65–74. doi:10.1016/0166-6851(86)90080-0. PMID 3095639. 

[edit] External links

The CAS registry number for this enzyme class is 105542-39-0.

• IUBMB entry for 2.6.1.68

• KEGG entry for 2.6.1.68

• BRENDA entry for 2.6.1.68

• NiceZyme view of 2.6.1.68

• EC2PDB: PDB structures for 2.6.1.68

• PRIAM entry for 2.6.1.68

• PUMA2 entry for 2.6.1.68

• IntEnz: Integrated Enzyme entry for 2.6.1.68

• MetaCyc entry for 2.6.1.68

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050155: ornithine(lysine) transaminase

• AMIGO entry for GO code 0050155: ornithine(lysine) transaminase